[D-Trp7,9,10]-Substance P TFA

CAS: F: C81H106F3N21O15S W: 1702.90

-Substance P TFA is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductan

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Bioactivity	[D-Trp7,9,10]-Substance P TFA is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance through nicotinic acetylcholine receptors[1].
Invitro	Substance P (SP)-related peptide, pGlu-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2, inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[2].
Name	[D-Trp7,9,10]-Substance P TFA
Sequence	Arg-Pro-Lys-Pro-Gln-Gln-Trp-Phe-Trp-Trp-Met-NH2
Shortening	RPKPQQWFWWM-NH2
Formula	C81H106F3N21O15S
Molar Mass	1702.90
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

H-D-Phe(4-F)-OH